A 96 well format test utilizing optimized lipid membranes and implemented on manual (Explorer) or automated (Evolution) liquid handling platforms.
Pharma companies worldwide confidently predict permeability through human skin, the GIT and BBB using Pion’s PAMPA Systems. Bring new drug products to market more inexpensively and faster with fewer downstream failures.
For increased magnitude response and better data integrity, there is also the option of using the The Gut-Box™. This is an important accessory that is designed with a built-in stirring mechanism, and is calibrated to specific speeds so that the PAMPA assay mimics the expected thickness of the aqueous boundary layer in the GIT.
Features:
- Spend less money with cost effective screening – less than $1per test
- Choose between scalable packages for various throughput needs and budgets
- Turnkey solution – Sole provider of complete PAMPA System
- Reduce in-vivo testing with predictive in-vitro testing
- Use proven and optimized GIT, BBB & Skin models
- Easy to use – Start testing quickly
- Predict permeability with sub-micromolar detection limit
- Create new models using PAMPA open platforms
- Comprehensive, integrated data processing & analysis software
- Easy integration with liquid handling platforms and detection systems
- Global support from world recognized permeability experts